The KH domain facilitates the substrate specificity and unwinding processivity of DDX43 helicase

The K-homology (KH) domain is a nucleic acid–binding domain present in many proteins. Recently, we found that the DEAD-box helicase DDX43 contains a KH domain in its N-terminus; however, its function remains unknown. Here, we purified recombinant DDX43 KH domain protein and found that it prefers bin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Yadav, Manisha, Singh, Ravi Shankar, Hogan, Daniel, Vidhyasagar, Venkatasubramanian, Yang, Shizhuo, Chung, Ivy Yeuk Wah, Kusalik, Anthony, Dmitriev, Oleg Y., Cygler, Miroslaw, Wu, Yuliang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949032/
https://ncbi.nlm.nih.gov/pubmed/33199368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015824
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