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A Distinct Triplex DNA Unwinding Activity of ChlR1 Helicase

Mutations in the human ChlR1 (DDX11) gene are associated with a unique genetic disorder known as Warsaw breakage syndrome characterized by cellular defects in genome maintenance. The DNA triplex helix structures that form by Hoogsteen or reverse Hoogsteen hydrogen bonding are examples of alternate D...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Guo, Manhong, Hundseth, Kristian, Ding, Hao, Vidhyasagar, Venkatasubramanian, Inoue, Akira, Nguyen, Chi-Hung, Zain, Rula, Lee, Jeremy S., Wu, Yuliang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335251/
https://ncbi.nlm.nih.gov/pubmed/25561740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634923
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