A Distinct Triplex DNA Unwinding Activity of ChlR1 Helicase

Mutations in the human ChlR1 (DDX11) gene are associated with a unique genetic disorder known as Warsaw breakage syndrome characterized by cellular defects in genome maintenance. The DNA triplex helix structures that form by Hoogsteen or reverse Hoogsteen hydrogen bonding are examples of alternate D...

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Vydáno v:J Biol Chem
Hlavní autoři: Guo, Manhong, Hundseth, Kristian, Ding, Hao, Vidhyasagar, Venkatasubramanian, Inoue, Akira, Nguyen, Chi-Hung, Zain, Rula, Lee, Jeremy S., Wu, Yuliang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335251/
https://ncbi.nlm.nih.gov/pubmed/25561740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634923
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