A Distinct Triplex DNA Unwinding Activity of ChlR1 Helicase

Mutations in the human ChlR1 (DDX11) gene are associated with a unique genetic disorder known as Warsaw breakage syndrome characterized by cellular defects in genome maintenance. The DNA triplex helix structures that form by Hoogsteen or reverse Hoogsteen hydrogen bonding are examples of alternate D...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Guo, Manhong, Hundseth, Kristian, Ding, Hao, Vidhyasagar, Venkatasubramanian, Inoue, Akira, Nguyen, Chi-Hung, Zain, Rula, Lee, Jeremy S., Wu, Yuliang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335251/
https://ncbi.nlm.nih.gov/pubmed/25561740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.634923
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