The DEAD-box protein DDX43 (HAGE) is a dual RNA-DNA helicase and has a K-homology domain required for full nucleic acid unwinding activity

The K-homology (KH) domain is a nucleic acid-binding domain present in many proteins but has not been reported in helicases. DDX43, also known as HAGE (helicase antigen gene), is a member of the DEAD-box protein family. It contains a helicase core domain in its C terminus and a potential KH domain i...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Talwar, Tanu, Vidhyasagar, Venkatasubramanian, Qing, Jennifer, Guo, Manhong, Kariem, Ahmad, Lu, Yi, Singh, Ravi Shankar, Lukong, Kiven Erique, Wu, Yuliang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
DNA and Chromosomes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481555/
https://ncbi.nlm.nih.gov/pubmed/28468824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.774950
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