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The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X
DEAD-box helicases (DDXs) regulate RNA processing and metabolism by unwinding short double-stranded (ds) RNAs. Sharing a helicase core composed of two RecA-like domains (D1D2), DDXs function in an ATP-dependent, non-processive manner. As an attractive target for cancer and AIDS treatment, DDX3X and...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6626043/ https://ncbi.nlm.nih.gov/pubmed/31300642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11083-2 |
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