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Structural basis for RNA duplex recognition and unwinding by the DEAD-box helicase Mss116p

DEAD-box proteins are the largest family of nucleic acid helicases and are crucial to RNA metabolism throughout all domains of life(1,2). They contain a conserved ‘helicase core’ of two RecA-like domains (domains 1 and 2; D1 and D2, respectively), which uses ATP to catalyze the unwinding of short RN...

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Detalhes bibliográficos
Main Authors: Mallam, Anna L., Campo, Mark Del, Gilman, Benjamin, Sidote, David J., Lambowitz, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465527/
https://ncbi.nlm.nih.gov/pubmed/22940866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11402
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