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Targeting opioid receptor signaling in depression: do we need selective κ opioid receptor antagonists?

The opioid receptors are a family of G-protein coupled receptors (GPCRs) with close structural homology. The opioid receptors are activated by a variety of endogenous opioid neuropeptides, principally β-endorphin, dynorphins, leu- and met-enkephalins. The clinical potential of targeting opioid recep...

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Detalhes bibliográficos
Publicado no:Neuronal Signal
Main Authors: Bailey, Sarah J., Husbands, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373229/
https://ncbi.nlm.nih.gov/pubmed/32714584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/NS20170145
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