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In vivo and in vitro characterization of naltrindole-derived ligands at the κ-opioid receptor
Accumulating evidence supports a role for κ−opioid receptor antagonists in the treatment of mood disorders. Standard κ-antagonists have an unusual pharmacodynamic action, with a single injection blocking receptor signalling for several weeks. Here, we have characterized the κ-selective properties of...
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| Publicado no: | J Psychopharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361741/ https://ncbi.nlm.nih.gov/pubmed/23118019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881112464828 |
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