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Characterization of BU09059: A Novel Potent Selective κ-Receptor Antagonist

[Image: see text] Kappa-opioid receptor (κ) antagonists are potential therapeutic agents for a range of psychiatric disorders. The feasibility of developing κ-antagonists has been limited by the pharmacodynamic properties of prototypic κ-selective antagonists; that is, they inhibit receptor signalin...

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Detalhes bibliográficos
Main Authors: Casal-Dominguez, Joseph J., Furkert, Daniel, Ostovar, Mehrnoosh, Teintang, Linnea, Clark, Mary J., Traynor, John R., Husbands, Stephen. M., Bailey, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963132/
https://ncbi.nlm.nih.gov/pubmed/24410326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn4001507
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