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Antidepressant‐like effects of BU10119, a novel buprenorphine analogue with mixed κ/μ receptor antagonist properties, in mice
BACKGROUND AND PURPOSE: The κ receptor antagonists have potential for treating neuropsychiatric disorders. We have investigated the in vivo pharmacology of a novel buprenorphine analogue, BU10119, for the first time. EXPERIMENTAL APPROACH: To determine the opioid pharmacology of BU10119 (0.3–3 mg·kg...
Enregistré dans:
| Publié dans: | Br J Pharmacol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016679/ https://ncbi.nlm.nih.gov/pubmed/28967123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14060 |
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