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Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice

Opiates have been used historically for the treatment of depression. Renewed interest in the use of opiates as antidepressants has focussed on the development of kappa opioid receptor (κ-receptor) antagonists. Buprenorphine acts as a partial μ-opioid receptor agonist and a κ-receptor antagonist. By...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Psychopharmacol
Päätekijät: Almatroudi, Abdulrahman, Husbands, Stephen M., Bailey, Christopher P., Bailey, Sarah J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075030/
https://ncbi.nlm.nih.gov/pubmed/26045511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881115586937
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