Peripheral administration of lactate produces antidepressant-like effects

In addition to its role as metabolic substrate that can sustain neuronal function and viability, emerging evidence supports a role for l-lactate as an intercellular signaling molecule involved in synaptic plasticity. Clinical and basic research studies have shown that major depression and chronic st...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Carrard, A, Elsayed, M, Margineanu, M, Boury-Jamot, B, Fragnière, L, Meylan, E M, Petit, J-M, Fiumelli, H, Magistretti, P J, Martin, J-L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794893/
https://ncbi.nlm.nih.gov/pubmed/27752076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.179
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