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Disrupting astrocyte–neuron lactate transfer persistently reduces conditioned responses to cocaine

A central problem in the treatment of drug addiction is the high risk of relapse often precipitated by drug-associated cues. The transfer of glycogen-derived lactate from astrocytes to neurons is required for long-term memory. Whereas blockade of drug memory reconsolidation represents a potential th...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Boury-Jamot, B, Carrard, A, Martin, J L, Halfon, O, Magistretti, P J, Boutrel, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960452/
https://ncbi.nlm.nih.gov/pubmed/26503760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.157
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