Norepinephrine stimulates glycogenolysis in astrocytes to fuel neurons with lactate

The mechanism of rapid energy supply to the brain, especially to accommodate the heightened metabolic activity of excited states, is not well-understood. We explored the role of glycogen as a fuel source for neuromodulation using the noradrenergic stimulation of glia in a computational model of the...

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Detaylı Bibliyografya
Yayımlandı:PLoS Comput Biol
Asıl Yazarlar: Coggan, Jay S., Keller, Daniel, Calì, Corrado, Lehväslaiho, Heikki, Markram, Henry, Schürmann, Felix, Magistretti, Pierre J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160207/
https://ncbi.nlm.nih.gov/pubmed/30161133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006392
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