Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity

[Image: see text] The first asymmetric total synthesis of three structures proposed for mycobacterial diacyl trehaloses, DAT(1), DAT(2), and DAT(3) is reported. The presence of two of these glycolipids, DAT(1) and DAT(3), within different strains of pathogenic M. tuberculosis was confirmed, and it w...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Holzheimer, Mira, Reijneveld, Josephine F., Ramnarine, Alexandrea K., Misiakos, Georgios, Young, David C., Ishikawa, Eri, Cheng, Tan-Yun, Yamasaki, Sho, Moody, D. Branch, Van Rhijn, Ildiko, Minnaard, Adriaan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372558/
https://ncbi.nlm.nih.gov/pubmed/32293864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00030
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados