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Generation of Recombinant Mammalian Selenoproteins through Genetic Code Expansion with Photocaged Selenocysteine

Selenoproteins contain the amino acid selenocysteine and are found in all domains of life. The functions of many selenoproteins are poorly understood, partly due to difficulties in producing recombinant selenoproteins for cell-biological evaluation. Endogenous mammalian selenoproteins are produced t...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Peeler, Jennifer C., Falco, Julia A., Kelemen, Rachel E., Abo, Masahiro, Chartier, Benjamin V., Edinger, Laura C., Chen, Jingjia, Chatterjee, Abhishek, Weerapana, Eranthie
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372505/
https://ncbi.nlm.nih.gov/pubmed/32330002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00147
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