Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens

Langerhans cells (LCs) are antigen-presenting cells that reside in the skin. They uniquely express high levels of the C-type lectin receptor Langerin (CD207), which is an attractive target for antigen delivery in immunotherapeutic vaccination strategies against cancer. We here assess a library of 20...

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Udgivet i:Front Cell Dev Biol
Main Authors: Li, Rui-Jun Eveline, Hogervorst, Tim P., Achilli, Silvia, Bruijns, Sven C. M., Spiekstra, Sander, Vivès, Corinne, Thépaut, Michel, Filippov, Dmitri V., van der Marel, Gijs A., van Vliet, Sandra J., Fieschi, Franck, Codée, Jeroen D. C., van Kooyk, Yvette
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371993/
https://ncbi.nlm.nih.gov/pubmed/32760719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00556
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