Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells

Many tumors display alterations in the biosynthetic pathways of glycosylation, resulting in increased expression of specific tumor-associated glycan structures. Expression of these altered glycan structures is associated with metastasis and poor prognosis. Antigen presenting cells can recognize tumo...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Zaal, Anouk, Li, R. J. Eveline, Lübbers, Joyce, Bruijns, Sven C. M., Kalay, Hakan, van Kooyk, Yvette, van Vliet, Sandra J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053379/
https://ncbi.nlm.nih.gov/pubmed/32161592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00305
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