Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells

Many tumors display alterations in the biosynthetic pathways of glycosylation, resulting in increased expression of specific tumor-associated glycan structures. Expression of these altered glycan structures is associated with metastasis and poor prognosis. Antigen presenting cells can recognize tumo...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Zaal, Anouk, Li, R. J. Eveline, Lübbers, Joyce, Bruijns, Sven C. M., Kalay, Hakan, van Kooyk, Yvette, van Vliet, Sandra J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053379/
https://ncbi.nlm.nih.gov/pubmed/32161592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00305
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