Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells

Many tumors display alterations in the biosynthetic pathways of glycosylation, resulting in increased expression of specific tumor-associated glycan structures. Expression of these altered glycan structures is associated with metastasis and poor prognosis. Antigen presenting cells can recognize tumo...

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Publicat a:Front Immunol
Autors principals: Zaal, Anouk, Li, R. J. Eveline, Lübbers, Joyce, Bruijns, Sven C. M., Kalay, Hakan, van Kooyk, Yvette, van Vliet, Sandra J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053379/
https://ncbi.nlm.nih.gov/pubmed/32161592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00305
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