Activation of the C-Type Lectin MGL by Terminal GalNAc Ligands Reduces the Glycolytic Activity of Human Dendritic Cells

Many tumors display alterations in the biosynthetic pathways of glycosylation, resulting in increased expression of specific tumor-associated glycan structures. Expression of these altered glycan structures is associated with metastasis and poor prognosis. Antigen presenting cells can recognize tumo...

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Publicado en:Front Immunol
Autores principales: Zaal, Anouk, Li, R. J. Eveline, Lübbers, Joyce, Bruijns, Sven C. M., Kalay, Hakan, van Kooyk, Yvette, van Vliet, Sandra J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053379/
https://ncbi.nlm.nih.gov/pubmed/32161592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00305
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