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Overproduction, purification and preliminary crystallographic analysis of the carbohydrate-recognition domain of human langerin
Langerin, a lectin that is specific to Langerhans cells, interacts with glycoconjugates through its carbohydrate-recognition domain (CRD). This carbohydrate binding occurs by an avidity-based mechanism that is enabled by the neck domain responsible for trimerization. Langerin binds HIV through its...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
International Union of Crystallography
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374187/ https://ncbi.nlm.nih.gov/pubmed/18259063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108001000 |
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