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Proteome activity landscapes of tumor cell lines determine drug responses

Integrated analysis of genomes, transcriptomes, proteomes and drug responses of cancer cell lines (CCLs) is an emerging approach to uncover molecular mechanisms of drug action. We extend this paradigm to measuring proteome activity landscapes by acquiring and integrating quantitative data for 10,000...

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出版年:Nat Commun
主要な著者: Frejno, Martin, Meng, Chen, Ruprecht, Benjamin, Oellerich, Thomas, Scheich, Sebastian, Kleigrewe, Karin, Drecoll, Enken, Samaras, Patroklos, Hogrebe, Alexander, Helm, Dominic, Mergner, Julia, Zecha, Jana, Heinzlmeir, Stephanie, Wilhelm, Mathias, Dorn, Julia, Kvasnicka, Hans-Michael, Serve, Hubert, Weichert, Wilko, Kuster, Bernhard
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371697/
https://ncbi.nlm.nih.gov/pubmed/32686665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17336-9
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