Peptide Level Turnover Measurements Enable the Study of Proteoform Dynamics

The coordination of protein synthesis and degradation regulating protein abundance is a fundamental process in cellular homeostasis. Today, mass spectrometry-based technologies allow determination of endogenous protein turnover on a proteome-wide scale. However, standard dynamic SILAC (Stable Isotop...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Zecha, Jana, Meng, Chen, Zolg, Daniel Paul, Samaras, Patroklos, Wilhelm, Mathias, Kuster, Bernhard
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930408/
https://ncbi.nlm.nih.gov/pubmed/29414762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000583
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