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Proteome activity landscapes of tumor cell lines determine drug responses
Integrated analysis of genomes, transcriptomes, proteomes and drug responses of cancer cell lines (CCLs) is an emerging approach to uncover molecular mechanisms of drug action. We extend this paradigm to measuring proteome activity landscapes by acquiring and integrating quantitative data for 10,000...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7371697/ https://ncbi.nlm.nih.gov/pubmed/32686665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17336-9 |
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