MAF1 is a chronic repressor of RNA polymerase III transcription in the mouse

Maf1(−/−) mice are lean, obesity-resistant and metabolically inefficient. Their increased energy expenditure is thought to be driven by a futile RNA cycle that reprograms metabolism to meet an increased demand for nucleotides stemming from the deregulation of RNA polymerase (pol) III transcription....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Bonhoure, Nicolas, Praz, Viviane, Moir, Robyn D., Willemin, Gilles, Mange, François, Moret, Catherine, Willis, Ian M., Hernandez, Nouria
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371695/
https://ncbi.nlm.nih.gov/pubmed/32686713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68665-0
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