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Metabolic programming a lean phenotype by deregulation of RNA polymerase III

As a master negative regulator of RNA polymerase (Pol) III, Maf1 modulates transcription in response to nutrients and stress to balance the production of highly abundant tRNAs, 5S rRNA, and other small noncoding RNAs with cell growth and maintenance. This regulation of Pol III transcription is impor...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Willis, Ian M., Moir, Robyn D., Hernandez, Nouria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275490/
https://ncbi.nlm.nih.gov/pubmed/30429315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815590115
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