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Human MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest

RNA polymerase III (Pol III) is tightly controlled in response to environmental cues, yet a genomic-scale picture of Pol III regulation and the role played by its repressor MAF1 is lacking. Here, we describe genome-wide studies in human fibroblasts that reveal a dynamic and gene-specific adaptation...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Orioli, Andrea, Praz, Viviane, Lhôte, Philippe, Hernandez, Nouria
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864463/
https://ncbi.nlm.nih.gov/pubmed/26941251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.201400.115
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