Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

MAF1 is a global repressor of RNA polymerase III transcription that regulates the expression of highly abundant noncoding RNAs in response to nutrient availability and cellular stress. Thus, MAF1 function is thought to be important for metabolic economy. Here we show that a whole-body knockout of Ma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Bonhoure, Nicolas, Byrnes, Ashlee, Moir, Robyn D., Hodroj, Wassim, Preitner, Frédéric, Praz, Viviane, Marcelin, Genevieve, Chua, Streamson C., Martinez-Lopez, Nuria, Singh, Rajat, Moullan, Norman, Auwerx, Johan, Willemin, Gilles, Shah, Hardik, Hartil, Kirsten, Vaitheesvaran, Bhavapriya, Kurland, Irwin, Hernandez, Nouria, Willis, Ian M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421982/
https://ncbi.nlm.nih.gov/pubmed/25934505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.258350.115
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg