Loss of the RNA polymerase III repressor MAF1 confers obesity resistance

MAF1 is a global repressor of RNA polymerase III transcription that regulates the expression of highly abundant noncoding RNAs in response to nutrient availability and cellular stress. Thus, MAF1 function is thought to be important for metabolic economy. Here we show that a whole-body knockout of Ma...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Genes Dev
Hlavní autoři: Bonhoure, Nicolas, Byrnes, Ashlee, Moir, Robyn D., Hodroj, Wassim, Preitner, Frédéric, Praz, Viviane, Marcelin, Genevieve, Chua, Streamson C., Martinez-Lopez, Nuria, Singh, Rajat, Moullan, Norman, Auwerx, Johan, Willemin, Gilles, Shah, Hardik, Hartil, Kirsten, Vaitheesvaran, Bhavapriya, Kurland, Irwin, Hernandez, Nouria, Willis, Ian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421982/
https://ncbi.nlm.nih.gov/pubmed/25934505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.258350.115
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky