Peripheral Effects of FAAH Deficiency on Fuel and Energy Homeostasis: Role of Dysregulated Lysine Acetylation

BACKGROUND: FAAH (fatty acid amide hydrolase), primarily expressed in the liver, hydrolyzes the endocannabinoids fatty acid ethanolamides (FAA). Human FAAH gene mutations are associated with increased body weight and obesity. In our present study, using targeted metabolite and lipid profiling, and n...

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Main Authors: Vaitheesvaran, Bhavapriya, Yang, Li, Hartil, Kirsten, Glaser, Sherrye, Yazulla, Stephen, Bruce, James E., Kurland, Irwin J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307749/
https://ncbi.nlm.nih.gov/pubmed/22442717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033717
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