Peripheral Effects of FAAH Deficiency on Fuel and Energy Homeostasis: Role of Dysregulated Lysine Acetylation

BACKGROUND: FAAH (fatty acid amide hydrolase), primarily expressed in the liver, hydrolyzes the endocannabinoids fatty acid ethanolamides (FAA). Human FAAH gene mutations are associated with increased body weight and obesity. In our present study, using targeted metabolite and lipid profiling, and n...

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Главные авторы: Vaitheesvaran, Bhavapriya, Yang, Li, Hartil, Kirsten, Glaser, Sherrye, Yazulla, Stephen, Bruce, James E., Kurland, Irwin J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307749/
https://ncbi.nlm.nih.gov/pubmed/22442717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033717
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