Role of the tumor suppressor IQGAP2 in metabolic homeostasis: Possible link between diabetes and cancer

Deficiency of IQGAP2, a scaffolding protein expressed primarily in liver leads to rearrangements of hepatic protein compartmentalization and altered regulation of enzyme functions predisposing development of hepatocellular carcinoma and diabetes. Employing a systems approach with proteomics, metabol...

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Autori principali: Vaitheesvaran, B., Hartil, K., Navare, A., Zheng, ÓBroin, P., Golden, A., Guha, Lee, WN., Kurland, I.J, Bruce, J. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169985/
https://ncbi.nlm.nih.gov/pubmed/25254002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-014-0639-9
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