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Metformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells

BACKGROUND: Metformin may exert the anticancer effect on multiple types of cancers and some potential mechanisms have been suggested. Our study was designed to determine the effect of metformin on the cell autophagy and autophagic flux via the AMPK-mTOR signaling pathway in human hepatocellular carc...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Gao, Chun, Fang, Long, Zhang, Hui, Zhang, Wei-Shuo, Li, Xiao-Ou, Du, Shi-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371564/
https://ncbi.nlm.nih.gov/pubmed/32765083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S257966
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