Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway

Random-pattern skin flaps are widely used to close defects in reconstructive and plastic surgeries; however, they are vulnerable to necrosis, particularly in the distal portion of the flap. Here, we examined the effects of metformin on flap survival and the mechanisms underlying these effects. Follo...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Int J Biol Sci
Главные авторы: Wu, Hongqiang, Ding, Jian, Li, Shihen, Lin, Jinti, Jiang, Renhao, Lin, Chen, Dai, Li, Xie, Chenglong, Lin, Dingsheng, Xu, Huazi, Gao, Weiyang, Zhou, Kailiang
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2019
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367544/
https://ncbi.nlm.nih.gov/pubmed/30745824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.29009
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы