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Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway

Random-pattern skin flaps are widely used to close defects in reconstructive and plastic surgeries; however, they are vulnerable to necrosis, particularly in the distal portion of the flap. Here, we examined the effects of metformin on flap survival and the mechanisms underlying these effects. Follo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Biol Sci
मुख्य लेखकों: Wu, Hongqiang, Ding, Jian, Li, Shihen, Lin, Jinti, Jiang, Renhao, Lin, Chen, Dai, Li, Xie, Chenglong, Lin, Dingsheng, Xu, Huazi, Gao, Weiyang, Zhou, Kailiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Ivyspring International Publisher 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367544/
https://ncbi.nlm.nih.gov/pubmed/30745824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.29009
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