FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival

Random-pattern skin flap is commonly used for surgical tissue reconstruction due to its ease and lack of axial vascular limitation. However, ischemic necrosis is a common complication, especially in distal parts of skin flaps. Previous studies have shown that FGF21 can promote angiogenesis and prote...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Zhou, Kailiang, Chen, Huanwen, Lin, Jinti, Xu, Hui, Wu, Hongqiang, Bao, Guodong, Li, Jiafeng, Deng, Xiangyang, Shui, Xiaolong, Gao, Weiyang, Ding, Jian, Xiao, Jian, Xu, Huazi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861244/
https://ncbi.nlm.nih.gov/pubmed/31740658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2105-0
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