Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement

Random-pattern skin flaps are commonly used and valuable tools in reconstructive surgery, however, post-operative random skin flap necrosis remains a major and common complication. Previous studies have suggested that activating autophagy, a major pathway for degradation of intracellular waste, may...

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Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Wu, Hongqiang, Chen, Huanwen, Zheng, Zhilong, Li, Jiafeng, Ding, Jian, Huang, Zihuai, Jia, Chang, Shen, Zitong, Bao, Guodong, Wu, Lingyun, Mamun, Abdullah Al, Xu, Huazi, Gao, Weiyang, Zhou, Kailiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745036/
https://ncbi.nlm.nih.gov/pubmed/31522191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1704-0
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