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Karyopherins And Condensates

Several aggregation prone RNA-binding proteins, including FUS, EWS, TAF15, hnRNP A1, hnRNP A2 and TDP-43, are mutated in neurodegenerative diseases. The nuclear-cytoplasmic distribution of these proteins is controlled by proteins in the Karyopherin family of nuclear transport factors (Kaps). Recent...

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Bibliografiska uppgifter
I publikationen:Curr Opin Cell Biol
Huvudupphovsmän: Springhower, Charis E., Rosen, Michael K., Chook, Yuh Min
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371519/
https://ncbi.nlm.nih.gov/pubmed/32474299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2020.04.003
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