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Karyopherins in Cancer

Malfunction of nuclear-cytoplasmic transport contributes to many diseases including cancer. Defective nuclear transport leads to changes in both the physiological levels and temporal-spatial location of tumor suppressors, proto-oncogenes and other macromolecules that in turn affect the tumorigenesis...

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Bibliographic Details
Published in:Curr Opin Cell Biol
Main Authors: Cagatay, Tolga, Chook, Yuh Min
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988925/
https://ncbi.nlm.nih.gov/pubmed/29414591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2018.01.006
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