Potential Role of Gut Microbiota, the Proto-Oncogene PIKE (Agap2) and Cytochrome P450 CYP2W1 in Promotion of Liver Cancer by Alcoholic and Nonalcoholic Fatty Liver Disease and Protection by Dietary Soy Protein

We have previously demonstrated promotion of diethylnitrosamine (DEN) initiated liver tumorigenesis aftre feeding diets high in fat or ethanol (EtOH) to male mice. This was accompanied by hepatic induction of the proto-oncogene PIKE (Agap2). Switch of dietary protein from casein to soy protein isola...

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Veröffentlicht in:Chem Biol Interact
Hauptverfasser: Ronis, Martin J, Mercer, Kelly E, Shankar, Kartik, Pulliam, Casey, Pedersen, Kim, Ingelman-Sundberg, Magnus, Friso, Simonetta, Samuelson, Derrick, Del Valle, Luis, Taylor, Chris, Welsh, David A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370542/
https://ncbi.nlm.nih.gov/pubmed/32417163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2020.109131
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