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Liver tumorigenesis is promoted by a high saturated fat diet specifically in male mice and is associated with hepatic expression of the proto-oncogene Agap2 and enrichment of the intestinal microbiome with Coprococcus

Liver cancer results in a high degree of mortality, especially among men. As fatty liver disease is a risk factor for development of hepatocellular carcinoma, we investigated the role of dietary fat type in tumor promotion by high-fat diets in mice after initiation with the chemical carcinogen dieth...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Pedersen, Kim B, Pulliam, Casey F, Patel, Aarshvi, Del Piero, Fabio, Watanabe, Tatiane T N, Wankhade, Umesh D, Shankar, Kartik, Hicks, Chindo, Ronis, Martin J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487682/
https://ncbi.nlm.nih.gov/pubmed/30325408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgy141
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