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MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment
Cells experiencing delays in mitotic progression are prone to undergo apoptosis unless they can exit mitosis before proapoptotic factors reach a critical threshold. Microtubule targeting agents (MTAs) arrest cells in mitosis and induce apoptotic cell death engaging the BCL2 network. Degradation of t...
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| Publicat a: | Cell Death Differ |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370223/ https://ncbi.nlm.nih.gov/pubmed/32015503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0503-6 |
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