Chargement en cours...
MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment
Cells experiencing delays in mitotic progression are prone to undergo apoptosis unless they can exit mitosis before proapoptotic factors reach a critical threshold. Microtubule targeting agents (MTAs) arrest cells in mitosis and induce apoptotic cell death engaging the BCL2 network. Degradation of t...
Enregistré dans:
| Publié dans: | Cell Death Differ |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370223/ https://ncbi.nlm.nih.gov/pubmed/32015503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0503-6 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|