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The NOXA–MCL1–BIM axis defines lifespan on extended mitotic arrest
Cell death on extended mitotic arrest is considered arguably most critical for the efficacy of microtubule-targeting agents (MTAs) in anticancer therapy. While the molecular machinery controlling mitotic arrest on MTA treatment, the spindle assembly checkpoint (SAC), appears well defined, the molecu...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Pub. Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423218/ https://ncbi.nlm.nih.gov/pubmed/25922916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7891 |
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