Anti-Cancer Activity of Acriflavine as Metabolic Inhibitor of OXPHOS in Pancreas Cancer Xenografts

PURPOSE: All currently available therapies for the treatment of pancreatic ductal adenocarcinoma (PDAC) show limited success. PDACs fast progression depends on the tumor characteristics and can be influenced by the microenvironment. The antibacterial drug acriflavine (ACF) has been shown to have ant...

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發表在:Onco Targets Ther
Main Authors: Bulle, Ashenafi, Dekervel, Jeroen, Deschuttere, Lise, Nittner, David, Van Cutsem, Eric, Verslype, Chris, van Pelt, Jos
格式: Artigo
語言:Inglês
出版: Dove 2020
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369416/
https://ncbi.nlm.nih.gov/pubmed/32764982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S245134
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