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Anti-Cancer Activity of Acriflavine as Metabolic Inhibitor of OXPHOS in Pancreas Cancer Xenografts

PURPOSE: All currently available therapies for the treatment of pancreatic ductal adenocarcinoma (PDAC) show limited success. PDACs fast progression depends on the tumor characteristics and can be influenced by the microenvironment. The antibacterial drug acriflavine (ACF) has been shown to have ant...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Bulle, Ashenafi, Dekervel, Jeroen, Deschuttere, Lise, Nittner, David, Van Cutsem, Eric, Verslype, Chris, van Pelt, Jos
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369416/
https://ncbi.nlm.nih.gov/pubmed/32764982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S245134
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