Gemcitabine induces Epithelial-to-Mesenchymal Transition in patient-derived pancreatic ductal adenocarcinoma xenografts

There is a lack of well-characterized models for pancreatic ductal adenocarcinoma (PDAC). PDAC itself is unique because of its pronounced tumor microenvironment that influences tumor progression, behavior and therapeutic resistance. Here we investigated, in patient-derived tumor xenograft (PDTX) mod...

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Détails bibliographiques
Publié dans:Am J Transl Res
Auteurs principaux: Bulle, Ashenafi, Dekervel, Jeroen, Libbrecht, Louis, Nittner, David, Deschuttere, Lise, Lambrecht, Diether, Van Cutsem, Eric, Verslype, Chris, van Pelt, Jos
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2019
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413274/
https://ncbi.nlm.nih.gov/pubmed/30899378
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