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Myopathic changes associated with psychomotor delay and seizures caused by a novel homozygous mutation in TBCK

INTRODUCTION: Biallelic mutations in TBC1-domain containing kinase (TBCK) lead to hypotonia, global developmental delay with severe cognitive and motor deficits, and variable presentation of dysmorphic facial features and brain malformations. It remains unclear whether hypotonia in these individuals...

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Bibliografske podrobnosti
izdano v:Muscle Nerve
Main Authors: Saredi, Simona, Cauley, Edmund S., Ruggieri, Alessandra, Spivey, Tyler M., Ardissone, Anna, Mora, Marina, Moroni, Isabella, Manzini, M. Chiara
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369155/
https://ncbi.nlm.nih.gov/pubmed/32363625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.26907
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