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Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains
BACKGROUND: Mutations in the gene encoding the cardiac voltage-gated sodium channel Na(v)1.5 cause various cardiac arrhythmias. This variety may arise from different determinants of Na(v)1.5 expression between cardiomyocyte domains. At the lateral membrane and T-tubules, Na(v)1.5 localization and fu...
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| Udgivet i: | Circ Arrhythm Electrophysiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Lippincott Williams & Wilkins
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7368852/ https://ncbi.nlm.nih.gov/pubmed/32536203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.119.008241 |
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