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Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains

BACKGROUND: Mutations in the gene encoding the cardiac voltage-gated sodium channel Na(v)1.5 cause various cardiac arrhythmias. This variety may arise from different determinants of Na(v)1.5 expression between cardiomyocyte domains. At the lateral membrane and T-tubules, Na(v)1.5 localization and fu...

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Detaylı Bibliyografya
Yayımlandı:Circ Arrhythm Electrophysiol
Asıl Yazarlar: Vermij, Sarah H., Rougier, Jean-Sébastien, Agulló-Pascual, Esperanza, Rothenberg, Eli, Delmar, Mario, Abriel, Hugues
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Lippincott Williams & Wilkins 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368852/
https://ncbi.nlm.nih.gov/pubmed/32536203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.119.008241
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