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Cellular hyper-excitability caused by mutations that alter the activation process of voltage-gated sodium channels
Voltage-gated sodium channels (Na(v)) are widely expressed as macro-molecular complexes in both excitable and non-excitable tissues. In excitable tissues, the upstroke of the action potential is the result of the passage of a large and rapid influx of sodium ions through these channels. Na(V) dysfun...
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| Published in: | Front Physiol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330716/ https://ncbi.nlm.nih.gov/pubmed/25741286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00045 |
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